The only thing these two amps share in common is that they're Integrated. The similarities pretty much stop there. While the 595 is a Class A amp you're only getting 60 watts.
Steve Guttenberg reviewd the Luxman on his YouTube channel:
https://www.youtube.com/watch?v=mx4RpRwrdgw
The Audio Excellence guys reviewed the McIntosh MA12000 on their YouTube channel:
https://www.youtube.com/watch?v=xUKz4gXJwKc
FWIW, YouTube has become utterly atrocious with all the infernal ads they force you to watch, but I digress.
Both amps are beautiful and undoubtedly provide a very sublime sonic experience. For my money I'd go with the MA12000, but admittedly I'm a bit of a Mc homer.
SF recommends power from 100 to 500 watts for your speakers (gorgeous ones BTW). Proper amp matching is part of that synergy thing you mentioned. Another check mark in the Mc's box.