[Formerly YB-2]

Good choice. CZ makes excellent firearms. Their CZ 75 custom shop target models have always been appealing for competition.
10mm packs a wallop and recoil, even in a semi-auto. Spend some time with your 75 and see if you can rent or test-fire a 1911 in 45ACP before purchasing one in 10mm. You may be able to shoot a 10mm as many indoor ranges have rental guns and may have one. You may find that the 45ACP is all you want. The Marines are fine with the 45 and the rest of the military with the 9mm. As defensive rounds have become better over the past 20yr, or so, the need for larger cartridges has diminished. Of course, if you are carrying in brown bear country, you can never have too large a handgun cartridge.